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Article

Caenorhabditis elegans NPR-1-mediated behaviors are suppressed in the presence of mucoid bacteria.

Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 2011

Reddy Kirthi C, Hunter Ryan C, Bhatla Nikhil, Newman Dianne K, Kim Dennis H

Abstract excerpt

Caenorhabditis elegans exhibits a diverse range of behaviors in response to bacteria. The presence of bacterial food influences C. elegans aerotaxis, aggregation, locomotion, and pathogen avoidance behaviors through the activity of the NPR-1 neuropeptide receptor. Here, we show that mucoid strains of bacteria that produce an exopolysaccharide matrix do not induce NPR-1-dependent behaviors. In the presence of...

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Identifiers

PMID: 21768378
DOI: 10.1073/pnas.1108265108
PMCID: PMC3150904

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