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Article

HDAC inhibition in the <i>cpfl1</i> mouse protects degenerating cone photoreceptors <i>in vivo</i>

15 Aug 2016

Abstract excerpt

Cone photoreceptor cell death as it occurs in certain hereditary retinal diseases is devastating, with the affected patients suffering from a loss of accurate and colour vision. Regrettably, these hereditary cone diseases are still untreatable to date. Thus, the identification of substances able to block or restrain cone cell death is of primary importance. We studied the neuroprotective effects of a histone...

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PMID: 28172811
DOI: 10.1093/hmg/ddw275

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