Article
Effect of leukoreduction on the omics phenotypes of canine packed red blood cells during refrigerated storage.
Journal of veterinary internal medicine - 1 Jan 2000
Miglio Arianna, Rocconi Francesca, Cremoni Valentina, D'Alessandro Angelo, Reisz Julie A, Maslanka Mark, Lacroix Ian S, Di Francesco Daniela, Antognoni Maria T, Di Tommaso Morena
Abstract excerpt
BACKGROUND: Red blood cell (RBC) storage promotes biochemical and morphological alterations, collectively referred to as storage lesions (SLs). Studies in humans have identified leukoreduction (LR) as a critical processing step that mitigates SLs. To date no study has evaluated the impact of LR on metabolic SLs in canine blood units using omics technologies. OBJECTIVE: Compare the lipid and metabolic profiles of...
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