Red cell membrane disorders: structure meets function.

doi:10.1182/blood.2019000946

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Article

Red cell membrane disorders: structure meets function.

Blood - 10 Sept 2020

Risinger Mary, Kalfa Theodosia A

Abstract excerpt

The mature red blood cell (RBC) lacks a nucleus and organelles characteristic of most cells, but it is elegantly structured to perform the essential function of delivering oxygen and removing carbon dioxide from all other cells while enduring the shear stress imposed by navigating small vessels and sinusoids. Over the past several decades, the efforts of biochemists, cell and molecular biologists, and...

Topics

Anemia, Hemolytic
Blood Proteins
Body Water
Cytoskeleton
Desiccation
Erythrocyte Membrane
Erythrocytes, Abnormal
Genetic Association Studies
Humans
Ion Channels
Models, Molecular
Mutation
Protein Conformation
Structure-Activity Relationship

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Identifiers

PMID: 32702754
DOI: 10.1182/blood.2019000946
PMCID: PMC7483429

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