Article
Seeking Goldilocks During Evolution of Drug Resistance.
PLoS biology - 1 Feb 2017
Sherlock Gavin, Petrov Dmitri A
Abstract excerpt
Speciation can occur when a population is split and the resulting subpopulations evolve independently, accumulating mutations over time that make them incompatible with one another. It is thought that such incompatible mutations, known as Bateson-Dobzhansky-Muller (BDM) incompatibilities, may arise when the two populations face different environments, which impose different selective pressures. However, a new...
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