Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors.

doi:10.1038/srep41875

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Article

Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors.

Scientific reports - 3 Feb 2017

Perretta-Tejedor Nuria, Fernández-Mateos Javier, García-Ortiz Luis, Gómez-Marcos Manuel A, Recio-Rodríguez José I, Agudo-Conde Cristina, Rodriguez-Sánchez Emiliano, Morales Ana I, López-Hernández Francisco J, López-Novoa José M, González-Sarmiento Rogelio, Martínez-Salgado Carlos

Abstract excerpt

Hypertension, diabetes and obesity are cardiovascular risk factors closely associated to the development of renal and cardiovascular target organ damage. VAV2 and VAV3, members of the VAV family proto-oncogenes, are guanosine nucleotide exchange factors for the Rho and Rac GTPase family, which is related with cardiovascular homeostasis. We have analyzed the relationship between the presence of VAV2 rs602990 and...

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Identifiers

PMID: 28157227
DOI: 10.1038/srep41875
PMCID: PMC5291103

Genes

VAV2
VAV3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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