Article
Embryological Results of Couples Undergoing ICSI-ET Treatments with Males Carrying the Single Nucleotide Polymorphism rs175080 of the MLH3 Gene.
International journal of molecular sciences - 2 Feb 2017
Anifandis George, Markandona Ourania, Dafopoulos Konstantinos, Messini Christina, Tsezou Aspasia, Dimitraki Marina, Georgoulias Panagiotis, Daponte Alexandros, Messinis Ioannis
Abstract excerpt
Human MLH3 (hMLH3) gene has been suggested to play a role in the DNA mismatch repair mechanism, while it may also be associated with abnormal spermatogenesis and subsequently male infertility. The aim of the present study was to investigate possible relationships between the single nucleotide polymorphism (SNP) rs175080 in the MLH3 gene of males and the embryological results in couples undergoing...
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