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Article

Single-nucleotide polymorphism rs 175080 in the MLH3 gene and its relation to male infertility.

Journal of assisted reproduction and genetics - 1 Dec 2015

Markandona Ourania, Dafopoulos Konstantinos, Anifandis George, Messini Christina I, Dimitraki Marina, Tsezou Aspasia, Georgoulias Panagiotis, Messinis Ioannis E

Abstract excerpt

PURPOSE: MLH3, a MutL homolog protein in mammals playing a role in DNA mismatch repair, is associated with spermatogenesis and male infertility. The purpose of the present study was to investigate the association of the single-nucleotide polymorphism (SNP), rs 175080 in the MLH3 gene, with sperm parameters in a Greek population. METHODS: The study included 300 men of couples undergoing in vitro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26520453
DOI: 10.1007/s10815-015-0594-z
PMCID: PMC4681734

Genes

MLH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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