Article
Six polymorphisms in genes involved in DNA double-strand break repair and chromosome synapsis: association with male infertility.
Systems biology in reproductive medicine - 1 Jan 2015
Zhang Xiaohui, Ding Min, Ding Xianping, Li Tianjun, Chen Honghan
Abstract excerpt
Four genes involved in DNA double-strand break repair and chromosome synapsis, i.e., testis expressed gene 11 (TEX11), testis expressed gene 15 (TEX15), mutL homolog 1 (MLH1), and homolog 3 (MLH3), play critical roles in genome integrity, meiotic recombination, and gametogenesis. We explored the possible association between single nucleotide polymorphisms (SNPs) in these genes and idiopathic male infertility...
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