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Article

The role of MSH5 C85T and MLH3 C2531T polymorphisms in the risk of male infertility with azoospermia or severe oligozoospermia.

Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2010

Xu Keqian, Lu Tingting, Zhou Hui, Bai Lihong, Xiang Yaoyun

Abstract excerpt

BACKGROUND: The mismatch repair proteins MSH5 and MLH3 play a crucial role in spermatogenesis. We tested this hypothesis by examining the contribution of functional polymorphisms in MSH5 C85T and MLH3 C2531T to the risk of male infertility. METHODS: We investigated Chinese patients, including 162 infertile individuals with idiopathic azoospermia or severe oligozoospermia, and 160 fertile men as controls. RESULTS:...

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Source

Identifiers

PMID: 19808033
DOI: 10.1016/j.cca.2009.09.038

Genes

MLH3
MSH5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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