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Article

A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs

3 Feb 2017

Abstract excerpt

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerative medicine. Reprogramming is a stepwise process with well-defined stages of initiation, maturation and stabilisation which are critically dependent on interactions between key pluripotency transcription factors, epigenetic regulators and signalling pathways. In this manuscript we have investigated the...

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PMID: 28155868
DOI: 10.1038/srep41693

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