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Article

Modulation of Pluripotency in the Porcine Embryo and iPS Cells

8 Nov 2012

Abstract excerpt

The establishment of the pluripotent ICM during early mammalian development is characterized by the differential expression of the transcription factors NANOG and GATA4/6, indicative of the epiblast and hypoblast, respectively. Differences in the mechanisms regulating the segregation of these lineages have been reported in many species, however little is known about this process in the porcine embryo. The aim of...

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PMID: 23145076
DOI: 10.1371/journal.pone.0049079

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