Article
Single-residue molecular switch for high-temperature dependence of vanilloid receptor TRPV3.
Proceedings of the National Academy of Sciences of the United States of America - 14 Feb 2017
Liu Beiying, Qin Feng
Abstract excerpt
Thermal transient receptor potential (TRP) channels, a group of ion channels from the transient receptor potential family, play important functions in pain and thermal sensation. These channels are directly activated by temperature and possess strong temperature dependence. Furthermore, their temperature sensitivity can be highly dynamic and use-dependent. For example, the vanilloid receptor transient receptor...
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