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Article

Activated Platelets Induce Endothelial Cell Activation via an Interleukin-1β Pathway in Systemic Lupus Erythematosus.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2017

Nhek Sokha, Clancy Robert, Lee Kristen A, Allen Nicole M, Barrett Tessa J, Marcantoni Emanuela, Nwaukoni Janet, Rasmussen Sara, Rubin Maya, Newman Jonathan D, Buyon Jill P, Berger Jeffrey S

Abstract excerpt

OBJECTIVE: Systemic lupus erythematosus (SLE) is associated with the premature development of cardiovascular disease. The platelet-endothelium interaction is important in the pathogenesis of cardiovascular disease. In this study, we investigated the platelet phenotype from patients with SLE and matched controls, and their effect on endothelial cells. APPROACH AND RESULTS: Platelet aggregability was measured in 54...

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Source

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Identifiers

PMID: 28153882
DOI: 10.1161/ATVBAHA.116.308126
PMCID: PMC5597960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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