Article
Using spatio-temporal surveillance data to test the infectious environment of children before type 1 diabetes diagnosis.
PloS one - 1 Jan 2017
Bougnères Pierre, Le Fur Sophie, Valtat Sophie, Kamatani Yoichiro, Lathrop Mark, Valleron Alain-Jacques
Abstract excerpt
The "hygiene hypothesis" postulates that reduced exposure to infections favours the development of autoimmunity and childhood type 1 diabetes (T1D). But on the other side, viruses, notably enteroviruses, are suspected to trigger T1D. The assessment of the possible relationships between infections and T1D still defies the classical tools of epidemiology. We report the methods and results of a geographical approach...
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