Article
Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study.
Viral immunology - 1 Dec 2015
Witsø Elisabet, Cinek Ondrej, Tapia German, Brorsson Caroline A, Stene Lars C, Gjessing Håkon K, Rasmussen Trond, Bergholdt Regine, Pociot Flemming M, Rønningen Kjersti S
Abstract excerpt
Enteroviruses have been suggested as triggers of type 1 diabetes (T1D). We aimed to assess whether established T1D susceptibility single nucleotide polymorphisms (SNPs) and candidate SNPs in innate immune genes were associated with the frequency of enterovirus infection in otherwise healthy children. Fifty-six established T1D SNPs and 97 other candidate immunity SNPs were typed in 419 children carrying the T1D...
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