Article
Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes.
Diabetes - 1 Feb 2014
Laitinen Olli H, Honkanen Hanna, Pakkanen Outi, Oikarinen Sami, Hankaniemi Minna M, Huhtala Heini, Ruokoranta Tanja, Lecouturier Valérie, André Philippe, Harju Raimo, Virtanen Suvi M, Lehtonen Jussi, Almond Jeffrey W, Simell Tuula, Simell Olli, Ilonen Jorma, Veijola Riitta, Knip Mikael, Hyöty Heikki
Abstract excerpt
The rapidly increasing incidence of type 1 diabetes implies that environmental factors are involved in the pathogenesis. Enteroviruses are among the suspected environmental triggers of the disease, and the interest in exploring the possibilities to develop vaccines against these viruses has increased. Our objective was to identify enterovirus serotypes that could be involved in the initiation of the disease...
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