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Article

Rapid detection of functional gene polymorphisms of TLRs and IL-17 using high resolution melting analysis.

Scientific reports - 2 Feb 2017

Teräsjärvi Johanna, Hakanen Antti, Korppi Matti, Nuolivirta Kirsi, Gröndahl-Yli-Hannuksela Kirsi, Mertsola Jussi, Peltola Ville, He Qiushui

Abstract excerpt

Genetic variations in toll-like receptors (TLRs) and IL-17A have been widely connected to different diseases. Associations between susceptibility and resistance to different infections and single nucleotide polymorphisms (SNPs) in TLR1 to TLR4 and IL17A have been found. In this study, we aimed to develop a rapid and high throughput method to detect functional SNPs of above mentioned proteins. The following most...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28148965
DOI: 10.1038/srep41522
PMCID: PMC5288650

Genes

TLR1
TLR4
TLR2
TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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