Article
A review of methods for detecting single-nucleotide polymorphisms in the Toll-like receptor gene family.
Biomarkers in medicine - 1 Sept 2021
Chauhan Alex, Pandey Nilesh, Jain Neeraj
Abstract excerpt
The Toll-like receptors play an essential role in immunity through targeting the pathogen-associated molecular patterns. Nucleotide variations in TLR genes, especially single-nucleotide polymorphisms, have been shown to alter host immune susceptibility to several infections and diseases. Since TLR genes' polymorphisms can be a promising biomarker, ongoing investigations aim to develop, optimize and validate SNP...
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