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Article

Angioimmunoblastic T-cell Lymphomas With the RHOA p.Gly17Val Mutation Have Classic Clinical and Pathologic Features.

The American journal of surgical pathology - 1 Mar 2016

Ondrejka Sarah L, Grzywacz Bartosz, Bodo Juraj, Makishima Hideki, Polprasert Chantana, Said Jonathan W, Przychodzen Bartlomiej, Maciejewski Jaroslaw P, Hsi Eric D

Abstract excerpt

Angioimmunoblastic T-cell lymphoma (AITL) is a nodal-based mature T-cell lymphoma with distinctive clinical symptomatology and histology. Research into its pathogenesis supports a cellular derivation from follicular helper T cells and overexpression of genes related to B cells, follicular dendritic cells, and vascular growth. Recently, a novel recurring somatic mutation in RHOA, encoding p.Gly17Val, was...

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Source

Identifiers

PMID: 26574844
DOI: 10.1097/PAS.0000000000000555

Genes

RHOA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Angioimmunoblastic T-cell Lymphomas With the RHOA p.Gly17Val Mutation Have Classic Clinical and Pathologic Features.PMID 26574844Read ↗

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