Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

* Coculture with Partial Digestion Notochordal Cell-Rich Nucleus Pulposus Tissue Activates Degenerative Human Nucleus Pulposus Cells.

Tissue engineering. Part A - 1 Aug 2017

Bai Xue-Dong, Li Xiao-Chuan, Chen Jia-Hai, Guo Zi-Ming, Hou Li-Sheng, Wang De-Li, He Qing, Ruan Di-Ke

Abstract excerpt

Recent studies suggested that notochordal cells (NCs) and NC-conditioned medium (NCCM) can stimulate cell viability and matrix production of nucleus pulposus cells (NPCs). However, the potential of notochordal cell-rich nucleus pulposus (NRNP) incorporating the native environment of the intervertebral disc (IVD) has not been evaluated. The objective of this study was to develop an optimal NRNP model and test...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coculture Techniques

Share to Extracellular Matrix

Share to Glycosaminoglycans

Share to Intervertebral Disc Degeneration

Share to Notochord

Share to Rabbits

Source

Identifiers

PMID: 28145804
DOI: 10.1089/ten.TEA.2016.0428

Genes

IVD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

* Coculture with Partial Digestion Notochordal Cell-Rich Nucleus Pulposus Tissue Activates Degenerative Human Nucleus Pulposus Cells.PMID 28145804Read ↗

Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 InteractionSemantic proximity Read ↗

Effects of nucleus pulposus cell-derived acellular matrix on the differentiation of mesenchymal stem cells.Semantic proximity Read ↗

Loss of notochordal cell phenotype in 3D-cell cultures: implications for disc physiology and disc repair.Semantic proximity Read ↗

Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study.Semantic proximity Read ↗

Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype.Semantic proximity Read ↗

Atelocollagen for culture of human nucleus pulposus cells forming nucleus pulposus-like tissue in vitro: Influence on the proliferation and proteoglycan production of HNPSV-1 cellsSemantic proximity Read ↗

Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotypeSemantic proximity Read ↗

Enrichment of committed human nucleus pulposus cells expressing chondroitin sulfate proteoglycans under alginate encapsulation.Semantic proximity Read ↗

Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells.Semantic proximity Read ↗

An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration.Semantic proximity Read ↗

Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration.Semantic proximity Read ↗

Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.