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Article

Sensitivity of notochordal disc cells to mechanical loading: an experimental animal study.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Jan 2010

Guehring Thorsten, Nerlich Andreas, Kroeber Markus, Richter Wiltrud, Omlor Georg W

Abstract excerpt

The immature disc nucleus pulposus (NP) consists of notochordal cells (NCs). With maturation NCs disappear in humans, to be replaced by chondrocyte-like mature NP cells (MNPCs); this change in cell phenotype coincidences with early signs of disc degeneration. The reasons for NC disappearance are...

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Source

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Identifiers

PMID: 19936803
DOI: 10.1007/s00586-009-1217-0
PMCID: PMC2899741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19936803-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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