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Article

FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia

31 Jan 2017

Abstract excerpt

promotes the development of resistant clones. Our results suggest that reduction of FZR1 increases therapeutic sensitivity of B-ALL and that transient rather than tonic inhibition of FZR1 may be a therapeutic strategy.

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Identifiers

PMID: 28143883
DOI: 10.1182/blood-2016-07-726216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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