Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fcγ receptor expression on splenic macrophages in adult immune thrombocytopenia.

Clinical and experimental immunology - 1 May 2017

Audia S, Santegoets K, Laarhoven A G, Vidarsson G, Facy O, Ortega-Deballon P, Samson M, Janikashvili N, Saas P, Bonnotte B, Radstake T R

Abstract excerpt

Splenic macrophages play a key role in immune thrombocytopenia (ITP) pathogenesis by clearing opsonized platelets. Fcγ receptors (FcγR) participate in this phenomenon, but their expression on splenic macrophages and their modulation by treatment have scarcely been studied in human ITP. We aimed to compare the phenotype and function of splenic macrophages between six controls and 24 ITP patients and between ITP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B7-2 Antigen
Share to Immunoglobulin G

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulins, Intravenous

Share to Phagocytosis

Share to Receptors, IgG

Share to Spleen

Share to Splenectomy

Share to Thrombocytopenia

Source

Open in PubMed Open full text

Identifiers

PMID: 28142207
DOI: 10.1111/cei.12935
PMCID: PMC5383444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fcγ receptor expression on splenic macrophages in adult immune thrombocytopenia.PMID 28142207Read ↗

FcγRIIIa polymorphism in pediatric immune thrombocytopenia: impact on clinical course and outcomeSemantic proximity Read ↗

FC gamma receptor polymorphisms in patients with immune thrombocytopenia.Semantic proximity Read ↗

The impact of Fc gamma receptor IIa and IIIa gene polymorphisms on the therapeutic response of rituximab in Egyptian adult immune thrombocytopenic purpura.Semantic proximity Read ↗

CD4+ T cell phenotypes in the pathogenesis of immune thrombocytopenia.Semantic proximity Read ↗

The presence of KIR2DS5 confers protection against adult immune thrombocytopenia.Semantic proximity Read ↗

Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia.Semantic proximity Read ↗

Immunomodulation by IVIg and the Role of Fc-Gamma Receptors: Classic Mechanisms of Action after all?Semantic proximity Read ↗

The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia.Semantic proximity Read ↗

Fcγ receptor gene polymorphisms in childhood immune thrombocytopenic purpura.Semantic proximity Read ↗

Current development of Fc gamma receptors (FcγRs) in diagnostics: a reviewSemantic proximity Read ↗

The role of CD8+ T cells in immune thrombocytopaenia (ITP)Semantic proximity Read ↗

Phenotypic and Functional Consequences of PLT Binding to Monocytes and Its Association with Clinical Features in SLE.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.