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Article

Phenotypic and Functional Consequences of PLT Binding to Monocytes and Its Association with Clinical Features in SLE.

International journal of molecular sciences - 29 Apr 2021

Mariscal Anaís, Zamora Carlos, Magallares Berta, Salman-Monte Tarek Carlos, Ortiz Mª Àngels, Díaz-Torné Cesar, Castellví Iván, Corominas Héctor, Vidal Silvia

Abstract excerpt

Platelets (PLTs) can modulate the immune system through the release of soluble mediators or through interaction with immune cells. Monocytes are the main immune cells that bind with PLTs, and this interaction is increased in several inflammatory and autoimmune conditions, including systemic lupus erythematosus (SLE). Our aim was to characterize the phenotypic and functional consequences of PLT binding to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33947017
DOI: 10.3390/ijms22094719
PMCID: PMC8125177

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