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Article

Quality Control by Isoleucyl-tRNA Synthetase of Bacillus subtilis Is Required for Efficient Sporulation.

Scientific reports - 31 Jan 2017

Kermgard Elizabeth, Yang Zhou, Michel Annika-Marisa, Simari Rachel, Wong Jacqueline, Ibba Michael, Lazazzera Beth A

Abstract excerpt

Isoleucyl-tRNA synthetase (IleRS) is an aminoacyl-tRNA synthetase whose essential function is to aminoacylate tRNAIle with isoleucine. Like some other aminoacyl-tRNA synthetases, IleRS can mischarge tRNAIle and correct this misacylation through a separate post-transfer editing function. To explore the biological significance of this editing function, we created a ileS(T233P) mutant of Bacillus subtilis that...

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Identifiers

PMID: 28139725
DOI: 10.1038/srep41763
PMCID: PMC5282499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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