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Article

Somatic mutations in cancer: Stochastic versus predictable.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Feb 2017

Gold Barry

Abstract excerpt

The origins of human cancers remain unclear except for a limited number of potent environmental mutagens, such as tobacco and UV light, and in rare cases, familial germ line mutations that affect tumor suppressor genes or oncogenes. A significant component of cancer etiology has been deemed stochastic and correlated with the number of stem cells in a tissue, the number of times the stem cells divide and a low...

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PMID: 28137366
DOI: 10.1016/j.mrgentox.2016.12.006

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CGA
APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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