Article
Genome-Wide Association of Copy Number Polymorphisms and Kidney Function.
PloS one - 1 Jan 2017
Li Man, Carey Jacob, Cristiano Stephen, Susztak Katalin, Coresh Josef, Boerwinkle Eric, Kao Wen Hong L, Beaty Terri H, Köttgen Anna, Scharpf Robert B
Abstract excerpt
Genome-wide association studies (GWAS) using single nucleotide polymorphisms (SNPs) have identified more than 50 loci associated with estimated glomerular filtration rate (eGFR), a measure of kidney function. However, significant SNPs account for a small proportion of eGFR variability. Other forms of genetic variation have not been comprehensively evaluated for association with eGFR. In this study, we assess...
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