Article
Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.
CNS neuroscience & therapeutics - 1 Apr 2017
Fang Wei, Fa Zhen-Zong, Xie Qun, Wang Gui-Zhen, Yi Jiu, Zhang Chao, Meng Guang-Xun, Gu Ju-Lin, Liao Wan-Qing
Abstract excerpt
INTRODUCTION: Fungal transversal across the brain microvascular endothelial cells (BMECs) is the essential step for the development of cryptococcal meningoencephalitis. Annexin A2 (AnxA2) is an important signaling protein involved in several intracellular processes such as membrane trafficking, endocytosis, and exocytosis. AIM: To investigate the roles and mechanism of AnxA2 during cryptococcal transversal of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
