Article

Primary Amoebic Meningoencephalitis caused by Complement C2 Deficiency

2026-02-02

Abstract excerpt

<h4>Background</h4> Primary amoebic meningoencephalitis (PAM) is a rapidly progressive and often fatal central nervous system infection caused by Naegleria fowleri . Despite widespread environmental exposure to this free-living amoeba, clinical disease is rare, suggesting that it requires not only exposure to the amoeba but also a host vulnerability. Yet, the immune mechanisms controlling protection vs. suscepti...

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Literature Corpus work: df1ad59f-9c10-5f79-95be-116cb6f8b7da
DOI: 10.64898/2026.01.31.26345168

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