Article
The Histone Modification Code in the Pathogenesis of Autoimmune Diseases.
Mediators of inflammation - 1 Jan 2017
Araki Yasuto, Mimura Toshihide
Abstract excerpt
Autoimmune diseases are chronic inflammatory disorders caused by a loss of self-tolerance, which is characterized by the appearance of autoantibodies and/or autoreactive lymphocytes and the impaired suppressive function of regulatory T cells. The pathogenesis of autoimmune diseases is extremely complex and remains largely unknown. Recent advances indicate that environmental factors trigger autoimmune diseases in...
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