Article
Epigenetic dynamics in immunity and autoimmunity.
The international journal of biochemistry & cell biology - 1 Oct 2015
Zhao Ming, Wang Zijun, Yung Susan, Lu Qianjin
Abstract excerpt
A tightly synchronized and spatial-temporal interaction among regulatory proteins within genomic DNA and chromatin is essential for cellular commitment and differentiation. During development and activation of the immune system, a complex regulatory network that involves induction of lineage instructive transcription factors, installation or removal of histone modifications and changes in DNA methylation patterns...
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