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Epigenetic modifications and epigenetic based medication implementations of autoimmune diseases.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Mar 2017

Ahmadi Majid, Gharibi Tohid, Dolati Sanam, Rostamzadeh Davood, Aslani Saeed, Baradaran Behzad, Younesi Vahid, Yousefi Mehdi

Abstract excerpt

Recent genome-wide association studies have documented a number of genetic variants to explain mechanisms underlying autoimmune diseases. However, the precise etiology of autoimmune diseases remains largely unknown. Epigenetic mechanisms like alterations in the post-translational modification of histones and DNA methylation may potentially cause a breakdown of immune tolerance and the perpetuation of autoreactive...

Topics

Animals
Autoimmune Diseases
DNA Methylation
Epigenesis, Genetic
Genetic Variation
Humans
Immune Tolerance

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28086135
DOI: 10.1016/j.biopha.2016.12.072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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