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Article

Discovery and characterisation of the automethylation properties of PRDM9.

The Biochemical journal - 7 Mar 2017

Koh-Stenta Xiaoying, Poulsen Anders, Li Rong, Wee John Liang Kuan, Kwek Perlyn Zekui, Chew Sin Yin, Peng Jianhe, Wu Liling, Guccione Ernesto, Joy Joma, Hill Jeffrey

Abstract excerpt

We have previously characterised the histone lysine methyltransferase properties of PRDM9, a member of the PRDM family of putative transcriptional regulators. PRDM9 displays broad substrate recognition and methylates a range of histone substrates, including octamers, core histone proteins, and peptides. In the present study, we show that PRDM9 performs intramolecular automethylation on multiple lysine residues...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28126738
DOI: 10.1042/BCJ20161067

Genes

PRDM9
SET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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