Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Psychosocial morbidity in TP53 mutation carriers: is whole-body cancer screening beneficial?

Familial cancer - 1 Jul 2017

McBride Kate A, Ballinger Mandy L, Schlub Timothy E, Young Mary-Anne, Tattersall Martin H N, Kirk Judy, Eeles Ros, Killick Emma, Walker Leslie G, Shanley Sue, Thomas David M, Mitchell Gillian

Abstract excerpt

Germline TP53 mutation carriers are at high risk of developing a range of cancers. Effective cancer risk management is an important issue for these individuals. We assessed the psychosocial impact in TP53 mutation carriers of WB-MRI screening as part of the Surveillance in Multi-Organ Cancer (SMOC+) protocol, measuring their unmet needs, anxiety and depression levels as well as cancer worry using psychological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Cancer-related Molecular Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Heterozygote

Share to Mass Screening

Share to Mutation

Share to Tumor Suppressor Protein p53

Share to Young Adult

Source

Identifiers

PMID: 28124295
DOI: 10.1007/s10689-016-9964-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Psychosocial morbidity in TP53 mutation carriers: is whole-body cancer screening beneficial?PMID 28124295Read ↗

Whole-body MRI surveillance in TP53 carriers is perceived as beneficial with no increase in cancer worry regardless of previous cancer: Data from the Swedish TP53 Study.Semantic proximity Read ↗

Psychosocial effects of whole-body MRI screening in adult high-risk pathogenic TP53 mutation carriers: a case-controlled study (SIGNIFY).Semantic proximity Read ↗

Surveillance recommendations for patients with germline TP53 mutations.Semantic proximity Read ↗

Cancer surveillance and distress among adult pathogenic TP53 germline variant carriers in Germany: A multicenter feasibility and acceptance survey.Semantic proximity Read ↗

Feasibility of a cancer screening program using multicancer early detection testing and whole-body magnetic resonance imaging in a high-risk population.Semantic proximity Read ↗

Baseline Surveillance in Li-Fraumeni Syndrome Using Whole-Body Magnetic Resonance Imaging: A Meta-analysis.Semantic proximity Read ↗

Psychosocial interventions and needs among individuals and families with Li-Fraumeni syndrome: A scoping review.Semantic proximity Read ↗

Baseline results from the UK SIGNIFY study: a whole-body MRI screening study in TP53 mutation carriers and matched controls.Semantic proximity Read ↗

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study.Semantic proximity Read ↗

Whole body magnetic resonance imaging (WB-MRI) and brain MRI baseline surveillance in TP53 germline mutation carriers: experience from the Li-Fraumeni Syndrome Education and Early Detection (LEAD) clinic.Semantic proximity Read ↗

Quality of life, anxiety and cancer worry following hereditary cancer testing: a 6-month Swedish follow-up study.Semantic proximity Read ↗

Psychological functioning in persons considering genetic counseling and testing for Li–Fraumeni syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.