Article
Whole body magnetic resonance imaging (WB-MRI) and brain MRI baseline surveillance in TP53 germline mutation carriers: experience from the Li-Fraumeni Syndrome Education and Early Detection (LEAD) clinic.
Familial cancer - 1 Apr 2018
Bojadzieva Jasmina, Amini Behrang, Day Suzanne F, Jackson Tiffiny L, Thomas Parijatham S, Willis Brandy J, Throckmorton Whitney R, Daw Najat C, Bevers Therese B, Strong Louise C
Abstract excerpt
Individuals with Li-Fraumeni syndrome (LFS) have a significantly increased lifetime cancer risk affecting multiple organ sites. Therefore, novel comprehensive screening approaches are necessary to improve cancer detection and survival in this population. The objective of this study was to determine the diagnostic performance of whole body MRI (WB-MRI) and dedicated brain MRI screening as part of a comprehensive...
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