Article
Activation of ventral tegmental area dopamine neurons produces wakefulness through dopamine D2-like receptors in mice.
Brain structure & function - 1 Aug 2017
Oishi Yo, Suzuki Yoshiaki, Takahashi Koji, Yonezawa Toshiya, Kanda Takeshi, Takata Yohko, Cherasse Yoan, Lazarus Michael
Abstract excerpt
A growing body of evidence suggests that dopamine plays a role in sleep-wake regulation, but the dopamine-producing brain areas that control sleep-wake states are unclear. In this study, we chemogenetically activated dopamine neurons in the ventral midbrain of mice to examine the role of these neurons in sleep-wake regulation. We found that activation of dopamine neurons in the ventral tegmental area (VTA), but...
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