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Article

Epistatic effect of TLR-1, -6 and -10 polymorphisms on organic dust-mediated cytokine response.

Genes and immunity - 1 Mar 2017

Smith L M, Weissenburger-Moser L A, Heires A J, Bailey K L, Romberger D J, LeVan T D

Abstract excerpt

Exposure to organic dust from agricultural environments is associated with inflammatory respiratory conditions. The putative causal agents in organic dust include viral, microbial and fungal components, which are recognized by the family of Toll-like receptors (TLRs) and drive host innate and adaptive responses. Our aim in this study was to determine whether responsiveness to organic dust among agricultural...

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Source

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Identifiers

PMID: 28123183
DOI: 10.1038/gene.2016.51
PMCID: PMC5407948

Genes

TLR1
TLR10
TLR6
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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