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Article

Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer.

Oncotarget - 21 Mar 2017

Donnarumma Elvira, Fiore Danilo, Nappa Martina, Roscigno Giuseppina, Adamo Assunta, Iaboni Margherita, Russo Valentina, Affinito Alessandra, Puoti Ilaria, Quintavalle Cristina, Rienzo Anna, Piscuoglio Salvatore, Thomas Renato, Condorelli Gerolama

Abstract excerpt

Cancer-associated fibroblasts (CAFs) are the major components of the tumor microenvironment. They may drive tumor progression, although the mechanisms involved are still poorly understood. Exosomes have emerged as important mediators of intercellular communication in cancer. They mediate horizontal transfer of microRNAs (miRs), mRNAs and proteins, thus affecting breast cancer progression. Differential expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28121625
DOI: 10.18632/oncotarget.14752
PMCID: PMC5386708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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