Article

Cancer-associated fibroblasts-derived exosomes suppresses immune cell function in breast cancer via miR-92/PD-L1 pathway

2020-03-23

Abstract excerpt

<h4>Background: </h4> Cancer associated fibroblasts (CAF) are important component in tumor microenvironment and has been reported contributes to tumor progression through many mechanisms, however, the detailed mechanism underling immune-suppression effect are not clearly defined. Methods In this study, human breast cancer-derived cancer associated fibroblasts was cultured, and CAF-derived exosomes in culture mediu...

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Literature Corpus work: 32c0cd9b-1606-5c68-9dea-f7c8cfb06753
DOI: 10.21203/rs.3.rs-18623/v1

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