Article

Exosomes derived from cancer-associated fibroblasts promote tumorigenesis, metastasis, chemoresistance of colorectal cancer cells by upregulating circ_0067557 to target Lin28A and Lin28B

2022-07-05

Abstract excerpt

Exosomes derived from cancer-associated fibroblasts (CAFs) may be crucial in colorectal cancer (CRC) progression, although the underlying function and mechanism of CAF-derived exosomes in CRC are still unclear. We used a circular RNA (circRNA) array to identify differentially expressed circRNAs in exosomes from normal fibroblasts (NFs) and CAFs. One differentially expressed circRNA was circ_0067557, whose expressi...

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Literature Corpus work: 1d06f829-e9ec-5830-b553-22603affe13d
DOI: 10.21203/rs.3.rs-1721959/v1

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