Article
Vascular endothelial growth factor A gene (VEGFA) polymorphisms and expression of VEGFA gene in lung cancer patients of Kashmir Valley (India).
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2012
Naik Niyaz A, Bhat Imtiyaz A, Afroze Dil, Rasool Roohi, Mir Hyder, Andrabi Syed Irtiza, Shah Sonaullah, Siddiqi Mushtaq A, Shah Zafar A
Abstract excerpt
The vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving tumor growth and metastasis. Polymorphisms in the VEGF gene may regulate VEGF production. In this case-control study, we investigated whether functional polymorphisms (+405 C > G and +936 C > T) in the VEGF gene are associated with the risk of lung cancer. Genomic DNA was isolated from the blood of 100 lung cancer patients...
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