Article
Vascular endothelial growth factor gene polymorphisms and risk of primary lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2005
Lee Su Jeong, Lee Sin Yeob, Jeon Hyo-Sung, Park Sun Ha, Jang Jin Sung, Lee Ga Young, Son Ji Woong, Kim Chang Ho, Lee Won Kee, Kam Sin, Park Rang Woon, Park Tae-In, Kang Young Mo, Kim In-San, Jung Tae Hoon, Park Jae Yong
Abstract excerpt
Angiogenesis is an essential process in the development, growth, and metastasis of malignant tumors including lung cancer. DNA sequence variations in the vascular endothelial growth factor (VEGF) gene may lead to altered VEGF production and/or activity, thereby causing interindividual differences in the susceptibility to lung cancer via their actions on the pathways of tumor angiogenesis. To test this hypothesis,...
Topics
- Aged
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Korea
- Lung Neoplasms
- Male