Four common vascular endothelial growth factor polymorphisms (-2578C>A, -460C>T, +936C>T, and +405G>C) in susceptibility to lung cancer: a meta-analysis.

doi:10.1371/journal.pone.0075123

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Article

Four common vascular endothelial growth factor polymorphisms (-2578C>A, -460C>T, +936C>T, and +405G>C) in susceptibility to lung cancer: a meta-analysis.

PloS one - 1 Jan 2013

Lin Ling, Cao Kejian, Chen Wenhu, Pan Xufeng, Zhao Heng

Abstract excerpt

BACKGROUND AND OBJECTIVE: Vascular endothelial growth factor (VEGF) is one of the key initiators and regulators of angiogenesis and it plays a vital role in the onset and development of malignancy. The association between VEGF gene polymorphisms and lung cancer risk has been extensively studied i...

Topics

Genetic Predisposition to Disease
Humans
Lung Neoplasms
Polymorphism, Single Nucleotide
Vascular Endothelial Growth Factor A

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