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Article

Predicting enhancer activity and variant impact using gkm-SVM.

Human mutation - 1 Sept 2017

Beer Michael A

Abstract excerpt

We participated in the Critical Assessment of Genome Interpretation eQTL challenge to further test computational models of regulatory variant impact and their association with human disease. Our prediction model is based on a discriminative gapped-kmer SVM (gkm-SVM) trained on genome-wide chromatin accessibility data in the cell type of interest. The comparisons with massively parallel reporter assays (MPRA) in...

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Identifiers

PMID: 28120510
DOI: 10.1002/humu.23185
PMCID: PMC5526747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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