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Article

NOX5: from basic biology to signaling and disease.

Free radical biology & medicine - 15 Feb 2012

Bedard Karen, Jaquet Vincent, Krause Karl-Heinz

Abstract excerpt

In mammals, the NADPH oxidase family of enzymes comprises seven members: NOXs 1-5, DUOX1, and DUOX2. All of these enzymes function to move an electron across cellular membranes, transferring it to oxygen to generate the superoxide anion. This generation of reactive oxygen species has important physiological and pathophysiological roles. NOX5 is perhaps the least well understood of these NOX isoforms, in part...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22182486
DOI: 10.1016/j.freeradbiomed.2011.11.023

Genes

NOX5
DUOX1
DUOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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