Article
The INSR rs2059806 single nucleotide polymorphism, a genetic risk factor for vascular and metabolic disease, associates with pre-eclampsia.
Reproductive biomedicine online - 1 Apr 2017
Andraweera Prabha H, Gatford Kathryn L, Dekker Gustaaf A, Leemaqz Shalem, Jayasekara Rohan W, Dissanayake Vajira H W, McCowan Lesley, Roberts Claire T
Abstract excerpt
Pre-eclampsia is a risk factor for later life vascular and metabolic diseases. This study postulates that this reflects a common genetic cause, and investigates whether the INSR rs2059806 single nucleotide polymorphism (SNP) (a risk factor for essential hypertension, type 2 diabetes and metabolic syndrome) is also associated with pre-eclampsia. The association of INSR rs2059806 with pre-eclampsia was tested in...
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