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Article

The genetics of pre-eclampsia and other hypertensive disorders of pregnancy.

Best practice & research. Clinical obstetrics & gynaecology - 1 Aug 2011

Williams Paula J, Broughton Pipkin Fiona

Abstract excerpt

Hypertension is the most frequent medical complication occurring during pregnancy. In this chapter, we aim to address the genetic contribution to these disorders, with specific focus on pre-eclampsia. The pathogenic mechanisms underlying pre-eclampsia remain to be elucidated; however, immune maladaptation, inadequate placental development and trophoblast invasion, placental ischaemia, oxidative stress and...

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Identifiers

PMID: 21429808
DOI: 10.1016/j.bpobgyn.2011.02.007
PMCID: PMC3145161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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