Article
Risk of pre-eclampsia in patients with a maternal genetic predisposition to common medical conditions: a case-control study.
BJOG : an international journal of obstetrics and gynaecology - 1 Jan 2021
Gray K J, Kovacheva V P, Mirzakhani H, Bjonnes A C, Almoguera B, Wilson M L, Ingles S A, Lockwood C J, Hakonarson H, McElrath T F, Murray J C, Norwitz E R, Karumanchi S A, Bateman B T, Keating B J, Saxena R
Abstract excerpt
OBJECTIVE: To assess whether women with a genetic predisposition to medical conditions known to increase pre-eclampsia risk have an increased risk of pre-eclampsia in pregnancy. DESIGN: Case-control study. SETTING AND POPULATION: Pre-eclampsia cases (n = 498) and controls (n = 1864) in women of European ancestry from five US sites genotyped on a cardiovascular gene-centric array. METHODS: Significant...
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