Article
PECAM-1 Leu125Val (rs688) Polymorphism and Diabetic Nephropathy in Caucasians with Type 2 Diabetes Mellitus.
Analytical cellular pathology (Amsterdam) - 1 Jan 2016
Završnik Matej, Kariž Stojan, Makuc Jana, Šeruga Maja, Cilenšek Ines, Petrovič Daniel
Abstract excerpt
Objectives. Platelet endothelial cell adhesion molecule-1 (PECAM-1) plays a key role in the transendothelial migration of circulating leukocytes during inflammation and in the maintenance of vascular endothelial integrity. We hypothesized that genetic variation in PECAM-1 gene could be associated with diabetic nephropathy (DN) and with the level of soluble PECAM-1 in Caucasians with type 2 diabetes mellitus...
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